Firenze Fiera- Fortezza da Basso Floorplan

Registered Attendees


Registered attendees (and speakers, organizers, etc.) will have access to the following items from their Account page:

  • Abstracts from speakers and poster sessions, including the joint meeting abstracts, available 30 days prior to the meeting (You can edit your own abstract from My Account page as well)

    NOTE: Abstract authors/submitters may choose to not have their abstract available online and in the secure mobile app until a week before the meeting.

  • Full participant list, including joint meeting participants
  • Printable Invoices and Invitation Letters
  • Scholarship Information
  • Lodging Information

Login to My Account page

Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment (M2)

Scientific Organizers: Erika L. Pearce, Sarah-Maria Fendt, Russell G. Jones and Peter F. Carmeliet


March 15—19, 2019

Firenze Fiera- Fortezza da Basso, Florence, Italy


Organized in collaboration with the following organizations - Cancer Research UK and Menarini International Foundation

Sponsored by Autolus Therapeutics


Abstract submission is now closed. Registered attendees may bring a poster onsite. Please contact our office at +1 800-253-0685; +1 970-262-1230 or email info@keystonesymposia.org if you are interested.
BEWARE of booking lodging through companies unaffiliated with Keystone Symposia. Click here for more details.

Keystone Symposia is committed to maintaining a positive and respectful environment at its meetings. To this end, please review and comply with our policies.

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Nov 28, 2018 [details]
Discounted Abstract Deadline: Nov 28, 2018 [details]
Abstract Deadline: Dec 11, 2018 [details]
Discounted Registration Deadline: Jan 17, 2019 [details]

If you have missed a deadline due to the US government shutdown, please contact our office.

Click here to view Cancellation Policy

Register Yourself Deadlines and Fees

Rates and Deadlines listed below are for the 2019-M2 "Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment" conference only.

*All deadlines end at 11:59 PM US Mountain Standard Time

Deadline Date Cost
Discounted Abstract Deadline
More details		 Before and On November 28, 2018 100.00 USD*
- 50.00 USD discount
Abstract Deadline
More details		 After November 28, 2018 until February 1, 2019 100.00 USD*
* 50.00 USD of Abstract fee deducted from your registration fee when you register for this meeting
Scholarship
More details		 November 28, 2018 n/a
Discounted NON-STUDENT Registration
More details		 Before and On January 17, 2019 945.00 USD
(includes 200.00 discount)
Regular NON-STUDENT Registration
More details		 After January 17, 2019 1145.00 USD
Discounted STUDENT Registration
More details		 Before and On January 17, 2019 720.00 USD
(includes 200.00 discount)
Regular STUDENT Registration
More details		 After January 17, 2019 920.00 USD

* Changes in payment type that result in a refund are subject to a processing fee.
* Currency exchange gains/losses are the responsibility of the registrant and the Keystone Symposia will accept no liability for money loss through bank charges, transfers or currency fluctuations.




Discounted Abstract Deadline: November 28, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time

Abstract Submission Fee: 100.00 USD*
Submission by this date receives 50.00 USD discount.
*50.00 USD will be applied to Registration Fee when you register

Abstract Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadlines. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract early allows us to:
  • submit your abstract to organizers to be considered for a short talk
  • accept your abstract online
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
(The Abstract Deadline: is December 11, 2018)

Global Health Travel Award Deadline:

*All deadlines end at 11:59 PM US Mountain Standard Time


Global Health Travel Award Details: You MUST complete your Global Health Travel Award appplication by the Global Health Travel Award Deadline and complete the other required steps (verify your contact information and submit a recommendation letter) to be considered for a travel award.


Click here to learn more about Global Health Travel Awards.

Scholarship Deadline: November 28, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Scholarship Details: You MUST submit your abstract by the Scholarship Deadline and complete the other required steps (submit a scholarship application and submit a mentor letter) to be considered for a scholarship.

Click here to learn more about Scholarships.

Abstract Deadline: December 11, 2018

*All deadlines end at 11:59 PM US Mountain Standard Time


Abstract Submission Fee: 100.00 USD*
*50.00 USD will be applied to Registration Fee when you register

Details: It is best to submit your abstract early. Abstract and registration spaces are limited and may fill prior to the abstract or discounted registration deadline. Submitting an abstract does not constitute or guarantee registration.

Submitting your abstract by the Abstract Deadline allows us to:

  • submit your abstract to organizers to be considered for a short talk
  • include your abstract on our website and in our secure mobile app
  • reserve your space at the meeting for a poster presentation.**
**Submitting an abstract does not constitute or guarantee registration.
Abstracts submitted after the Abstract Deadline will NOT be considered for a short talk.

(Discounted Abstract Deadline: is November 28, 2018)

Discounted Registration Deadline: January 17, 2019

*All deadlines end at 11:59 PM US Mountain Standard Time


Registration Fee: 945.00 USD* (includes 200.00 USD discount)
Student Registration Fee: 720.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

After the Discounted Registration Deadline:


Registration Fee: 1145.00 USD*
Student Registration Fee: 920.00 USD* (must complete student verification form)

*Includes 50.00 USD of your abstract submission fee

Registration spaces are limited and may fill prior to discounted registration deadline.

Please be advised that some meeting participants have received calls and emails from a number of different housing services, including "Exhibitors Housing Services," “Expo Housing Services,” "Global Housing," etc. THESE COMPANIES ARE NOT AFFILIATED WITH KEYSTONE SYMPOSIA and are not authorized by Keystone Symposia to contact you. These companies may tell you that the meeting is filling, without any actual knowledge to that effect, and pressure you into giving them your credit card number to make a lodging reservation with them.

We highly recommend that you not make a reservation with these companies or any other housing service! These companies' representations to participants have been misleading. Please report any calls or correspondence you might have received to Keystone Symposia and book only through lodging links in your Keystone Symposia account, an established travel agency or directly with the hotel(s) listed on our website.
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Friday, March 15 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Tuesday, March 19 with a closing plenary session from 16:00 to 18:00, followed by a social hour and entertainment. We recommend return travel on Wednesday, March 20 in order to fully experience the meeting.

FRIDAY, MARCH 15

16:00—20:00
Arrival and Registration

Fureria
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Arsenale

SATURDAY, MARCH 16

08:00—08:30
Poster Setup

Arsenale
08:30—18:00
Poster Viewing

Arsenale
08:30—09:30
Welcome and Keynote Address
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Erika L. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany

Charles Swanton, Francis Crick Institute, UK
Chromosomal Instability and Genome Plasticity in Cancer Evolution, Immune Evasion and Metastasis

09:30—12:00
Interactions via the Tumor Microenvironment
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Sarah-Maria Fendt, VIB Leuven, Belgium

Massimiliano Mazzone, KU Leuven – VIB, Belgium
Immunometabolism in Cancer and Other Diseases

Coffee Break

Shizhen Emily Wang, University of California, San Diego, USA
Secreted miRNAs Reprogram Metabolism in the Tumor Niche

Karen H. Vousden, Francis Crick Institute, UK
ROS Regulation and Cancer Progression

Samuel F. Bakhoum, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Chromosomal Instability Promotes Metastasis through a Cytosolic DNA Response and Modulation of the Immune Microenvironment

Li Yang, NCI, National Institutes of Health, USA
Short Talk: DNMT3B Induction at Distant Site Promotes Breast Cancer Metastasis through Epigenetic Reprogramming

12:00—13:00
Lunch

Arsenale
13:00—15:30
Poster Session 1

Arsenale
15:30—16:00
Coffee Available

Arsenale
16:00—18:00
Mitochondria and Oxidative Stress in Cancer Metastasis and Immunity
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA

Erika L. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany
Mitochondrial Integrity Regulated by FABP5 is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Marcia C. Haigis, Harvard Medical School, USA
New Functions for Metabolic Byproducts in the Tumor Microenvironment

Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA
Metabolic Enablers of Cancer Progression

Zachary T. Schafer, University of Notre Dame, USA
Short Talk: Resistance to PD-1 Checkpoint Inhibitors Is Associated with Defective RIPK1-Mediated Mitophagy

Alexei Vazquez, CRUK Beatson Institute, UK
Short Talk: Formate Links Glycolysis to Oxidative Phosphorylation

18:00
On Own for Dinner
No registration fees are used to fund alcohol served at this function.


SUNDAY, MARCH 17

08:30—11:45
Cancer and Immunity in the Tumor Microenvironment
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Georgia Hatzivassiliou, Genentech, Inc., USA

Russell G. Jones, Van Andel Research Institute, USA
Essential Nutrients for Effector T Cell Expansion

Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Microenvironmental Determinants of Tumor Metabolism

Coffee Break

Giuseppe Matarese, Università degli Studi di Napoli Federico II, Italy
Regulatory T Cells as Suppressors of Anti-Tumor Immunity

Iannis Aifantis, New York University School of Medicine, USA
Mapping the Bone Marrow Microenvironment in Single Cell Resolution

Fabio Grassi, Institute for Research in Biomedicine, Switzerland
Short Talk: Senescence Induction by the ATP-Gated P2X7 Receptor Limits T Cell Effector Response in the Tumor Microenvironment

Paula D. Bos, Virginia Commonwealth University, USA
Short Talk: Regulatory T Cells Promote Breast Cancer Progression and Metastasis by Functional Reprogramming of Bone Marrow-Derived Cell Populations

Zachary Bacigalupa, Vanderbilt University Medical Center, USA
Short Talk: Targeting ACSS2 Inhibits HIF-2alpha Signaling and Stimulates the Anti-Tumor Immune Response in ccRCC

11:45—16:00
On Own for Lunch

11:15—13:00
Poster Setup

Arsenale
13:00—22:00
Poster Viewing

Arsenale
13:30—15:30
Workshop

Basilica
* Julian J. Lum, British Columbia Cancer Agency, Canada

Ho-Young Lee†, Seoul National University, South Korea
The Interplay between Slow-Cycling Chemoresistant Cancer Cells and Fibroblasts in Tumor Microenvironment Mediates Tumor Recurrence in Lung Cancer

Julianna Blagih, Francis Crick Institute, UK
Loss of p53 in Tumor Cells Promotes Immune-Tolerance through Modulation of the Innate and Adaptive Immune Responses

Medhi Wangpaichitr, Miami VA Hospital, USA
Kynurenine Metabolism in Cisplatin-Resistant Lung Cancer

Nuzhat Ahmed, Fiona Elsey Cancer Research Institute, Australia
Metabolic and Immune Regulatory Signatures in Chemoresistant Ovarian Cancer Stem Cells

David R. Soto-Pantoja, Wake Forest School of Medicine, USA
Metabolic Endpoints as Biomarkers of Immune Checkpoint Therapy Response

Chia-Ning Shen, Academia Sinica, Taiwan
Mitochondrial OXPHOS Activity Is Required for Lung Metastatic Colonization of Pancreatic Cancer

Madhusudhanan Sukumar, NCI, National Institutes of Health, USA
Mitochondrial Uncoupling Protein 2 (UCP2) Regulates T Cell Longevity and Anti-Tumor Function

Jing Fan, University of Wisconsin-Madison, USA
Two-Stage Remodeling of Mitochondrial Metabolism in Macrophages Over a Course of Immune Response

15:30—16:00
Coffee Available

Arsenale
16:00—18:00
Metastasis, Tumor Vessels and Immunity
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Massimiliano Mazzone, KU Leuven – VIB, Belgium

Peter F. Carmeliet, University of Leuven, VIB, Belgium
Angiogenesis Revisited: Role and (Therapeutic) Implications of Endothelial Metabolism

Michael Potente, Max Planck Institute for Heart and Lung Research, Germany
Metabolic Activity and Growth State in the Vascular Endothelium

Bin-Zhi Qian, University of Edinburgh, UK
Macrophage Heterogeneity in Breast Cancer Metastasis

Sophia Y. Lunt, Michigan State University, USA
Short Talk: Sialic Acid Metabolism Is a Key Driver of Breast Cancer Metastasis

Andreas Fischer, German Cancer Research Center, Germany
Short Talk: Angiocrine Signals Promote Metastasis

18:00—19:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Arsenale
18:30—21:00
Poster Session 2

Arsenale

MONDAY, MARCH 18

08:00—08:30
Poster Setup

Arsenale
08:30—16:00
Poster Viewing

Arsenale
08:30—11:45
Therapeutic Strategies for Metabolism and Immune Modulation
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Giuseppe Matarese, Università degli Studi di Napoli Federico II, Italy

Katya Marjon, Agios Pharmaceuticals, USA
Therapeutics Targets in Cancer Metabolism

Tim F. Greten, NCI, National Institutes of Health, USA
Targeting the Inflammation – Cancer Axis

Coffee Break

Georgia Hatzivassiliou, Genentech, Inc., USA
Dissecting the Impact of NRF2 Activation on Lung Adenocarcinoma Biology, Immune Contexture and Patient Outcomes

Gabriele A.I. Bergers, University of Leuven, Belgium
Constructing Tumor Vessels to Enhance Immunity

Julian J. Lum, British Columbia Cancer Agency, Canada
Short Talk: Understanding the Metabolome of Human TIL for Cancer Immunotherapy

Fabricio Loayza-Puch, Deutsches Krebsforschungszentrum, Germany
Short Talk: Targeting Proline Availability in Metastatic Breast Cancer

Gus Zeiner, Chimera Bioengineering, USA
Short Talk: A Metabolism-Triggered, Localized Payload Delivery System for T Cell Therapies

11:45—13:00
Lunch

Arsenale
13:00—15:30
Poster Session 3

Arsenale
15:30—16:00
Coffee Available

Arsenale
16:00—18:00
Stem Cells in Inflammation, Cancer and Metastasis
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Iannis Aifantis, New York University School of Medicine, USA

Elaine V. Fuchs, Rockefeller University, USA
Skin Stem Cells in Inflammation and Cancer

Mohamed Bentires-Alj, University Hospital Basel, Switzerland
Cancer Targeted Therapy and Tumor Heterogeneity: Act Locally, Think Globally

Robert A. Weinberg, Massachusetts Institute of Technology, USA
Metastasis and the EMT

Guy Roukens, University Medical Center Utrecht, Netherlands
Short Talk: SOX4 Is Required for Maintaining Stem Cell Identity in Mammary Tumors

Binwu Tang, NCI, National Institutes of Health, USA
Short Talk: Elucidating the Role of Breast Cancer Stem Cells in Early Metastasis through Direct Visualization and Quantitation

18:00
On Own for Dinner
No registration fees are used to fund alcohol served at this function.


TUESDAY, MARCH 19

08:30—11:45
Metabolism Meets Cancer Metastasis
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Michael Potente, Max Planck Institute for Heart and Lung Research, Germany

M. Celeste Simon, University of Pennsylvania, USA
Metabolic Symbioses in the Tumor Micorenvironment

Sohail F. Tavazoie, Rockefeller University, USA
Innate Immune and Metabolic Regulation of Metastatic Progression

Coffee Break

Sarah-Maria Fendt, VIB Leuven, Belgium
Cancer Metabolism during Metastasis Formation

Arkaitz Carracedo, Center for Cooperative Research in Biosciences, Spain
Signaling and Metabolic Plasticity in the Process of Prostate Cancer Metastasis

Ana Patricia Gomes, Weill Cornell Medicine, USA
Short Talk: Age-Induced Methylmalonic Acid Accumulation Promotes Cancer Progression and Metastasis Formation

Emily Jane Kay, Beatson Institute, UK
Short Talk: Pyruvate Dehydrogenase: The Key to Epigenetic Regulation of Mammary CAFs

Yulia Panina, Francis Crick Institute, UK
Short Talk: Using Mass Spectrometry Imaging to Identify Metabolic Adaptations during Metastasis of MYC-Driven Tumors

11:45—17:00
On Own for Lunch

15:30—16:00
Coffee Available

Arsenale
16:00—17:45
Commensal Interactions: Implications for Immunity and Cancer
Registered attendees can view abstracts starting on 02/15/2019

Basilica
* Russell G. Jones, Van Andel Research Institute, USA

Filipe J. Gomes Cabreiro, University College London, UK
Host-Microbe-Drug-Nutrient Interactions- A Holistic Approach for Cancer Treatment

Jennifer Ann Wargo, University of Texas MD Anderson Cancer Center, USA
The Gut Microbiome and PD-1 Therapy in Melanoma

Nicholas Chia, Mayo Clinic, USA
Distinct Microbes, Metabolites and Ecologies Define the Microbiome in Deficient and Proficient Mismatch Repair Colorectal Cancers

17:45—18:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Registered attendees can view abstracts starting on 02/15/2019

Basilica
18:00—19:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Arsenale
19:00—22:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Arsenale

WEDNESDAY, MARCH 20

 
Departure


*Session Chair †Invited, not yet responded.


Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Autolus Therapeutics Organized in collaboration with Cancer Research UK
Menarini International Foundation
 

We gratefully acknowledge additional support from these exhibitors at this conference:

Don Whitley Scientific Limited Fluidigm UK LTD.
HypOxygen 10x Genomics
Please stop by to meet these exhibitors during the conference.

We gratefully acknowledge additional support for this conference from:

Agilent GeneTex, Inc.
InvivoGen
 

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Genentech, Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations

If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676